A complex systems approach to cancer understanding

Welcome

Introduction

Sara Franceschelli (IXXI); Olivier Gandrillon (BioSyL); Marc Billaud (Plascan)

Plasticity

Chair: Maria Ouzounova

› Cellular plasticity within the tumor ecosystem: heterotypic models to interrogate tumor and tumor microenvironment interactions - 14:15-15:15 (1h)

› Data driven mechanistic modeling of oxygen distribution and hypoxia profile in tumor microenvironment - Pawan Kumar 15:15-15:30 (15min)

Coffee break

Disorder

Chair: Sara Franceschelli

› From ‘Order-from-Order' to ‘Order-from-Disorder': Towards a Post-Schrödingerian View of the Cell - Daniel J. Nicholson, George Mason University 16:00-17:00 (1h)

› Histological and transcriptomic cartography identify S100B-FolliculoStem cells as a candidate signalling hub that may drive pituitary tumour behaviour - Philippe Bertolino 17:00-17:15 (15min)

Uniqueness

Chair: Bertrand Nadel

› Four tumor micro-environmental niches explain a continuum of inter-patient variation in the macroscopic cellular composition of breast tumors. - 17:15-18:15 (1h)

Cocktail