Planning

Week Mon. 17 Tue. 18 List

	Mon. 17	Tue. 18
08:00 09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00	Welcome 13:30 - 14:00 (30min) Welcome Introduction 14:00 - 14:15 (15min) Introduction Sara Franceschelli (IXXI); Olivier Gandrillon (BioSyL); Marc Billaud (Plascan) Plasticity 14:15 - 15:30 (1h15) Plasticity Chair: Maria Ouzounova › Cellular plasticity within the tumor ecosystem: heterotypic models to interrogate tumor and tumor microenvironment interactions - 14:15-15:15 (1h) › Data driven mechanistic modeling of oxygen distribution and hypoxia profile in tumor microenvironment - Pawan Kumar 15:15-15:30 (15min) Coffee break 15:30 - 16:00 (30min) Coffee break Disorder 16:00 - 17:15 (1h15) Disorder Chair: Sara Franceschelli › From ‘Order-from-Order' to ‘Order-from-Disorder': Towards a Post-Schrödingerian View of the Cell - Daniel J. Nicholson, George Mason University 16:00-17:00 (1h) › Histological and transcriptomic cartography identify S100B-FolliculoStem cells as a candidate signalling hub that may drive pituitary tumour behaviour - Philippe Bertolino 17:00-17:15 (15min) Uniqueness 17:15 - 18:15 (1h) Uniqueness Chair: Bertrand Nadel › Four tumor micro-environmental niches explain a continuum of inter-patient variation in the macroscopic cellular composition of breast tumors. - 17:15-18:15 (1h) Cocktail 18:15 - 19:30 (1h15) Cocktail	Stemness 8:30 - 10:00 (1h30) Stemness Chair: Marc Billaud › Cancer stem cells : what if stemness is a systemic property? - LUCIE LAPLANE, CNRS, University Paris I Panthéon-Sorbonne 08:30-09:30 (1h) › Mathematical modeling of CLL dynamics in patients under Ibrutinib treatment - Chloe Audebert 09:30-09:45 (15min) › From gene regulatory network inference to multiscale modeling: understanding the crosstalk between immune and cancer cells in Chronic Lymphocytic Leukemia - Malvina Marku 09:45-10:00 (15min) Coffee break 10:00 - 10:30 (30min) Coffee break Failing promises - Sponsored by ARC 10:30 - 12:00 (1h30) Failing promises - Sponsored by ARC Chair: Pierre Sujobert › Re-programming organisms, from cancer to Evolution: a myth resisting acknowledged "debacles"; which alternative ways? - 10:30-11:30 (1h) › Predicting regrowth of low-grade gliomas after radiotherapy - Stephane Plaszczynski 11:30-11:45 (15min) › B-cells kinetics after acute depletion following brain irradiation in preclinical context: a semi-mechanistic modeling and simulation approach - Thao-Nguyen Pham 11:45-12:00 (15min) Lunch 12:00 - 13:30 (1h30) Lunch Multiscale 13:30 - 14:30 (1h) Multiscale Chair: Pierre Martinez › From a mathematical model of a unique tumour cell to a model of a dynamic population of interacting cells - Laurence Calzone, Institut curie 13:30-14:30 (1h) Round table 14:30 - 15:30 (1h) Round table Coffee break 15:30 - 16:00 (30min) Coffee break Dynamics 16:00 - 17:05 (1h05) Dynamics Chair: Olivier Gandrillon › What does not kill me makes me stronger - dynamic instability and non-genetic plasticity in Tumor Progression - Sui Huang, ISB, Seattle 16:00-17:00 (1h)

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